Curriculum vitae with track record
ROLE IN THE PROJECT – HEAD of Research group:
Bergen CellStress, Tissue Engineering and Simulation in Biomedicine – BeCSTESim in Biomedicine
Project manager x Project partner ☐
PERSONAL INFORMATION
Family name, First name: Bjørkum, Alvhild Alette
Date of birth: 10.02.1962
Sex: woman
Nationality: Norwegian
Researcher unique identifier(s) (ORCID, ResearcherID, etc.): Bjorkum AA Google Scholar https://scholar.google.no/scholar?hl=no&as_sdt=0%2C5&q=bj%C3%B8rkum+alvhild&oq=
URL for personal web site: https://www.hvl.no/person/?user=3600064 and https://www.uib.no/en/rg/sc
EDUCATION
1996 PhD: Disputation date: 26*.05.1996* Ph.D. (Dr. Sci.) Neurophysiology, Department of Physiology, Medical Faculty, University of Bergen, Norway
1986 Master: M.Sci. (Cand. scient.) Human and zoological physiology, Department of Physiology, Medical Faculty, University of Bergen, Norway
CURRENT AND PREVIOUS POSITIONS
2002-2021 Associate Professor, Department of Biomedical Laboratory Sciences and Chemical Engineering, Faculty of Engineering, Bergen University College, Norway AND from 2017 Faculty of Engineering and Science, Western Norway University of Applied Sciences, Bergen, Norway
2001 Research coordinator, Department of Health, Bergen University Research Foundation
1999- Postdoctoral stipend from The Norwegian Research Council.
1998- Visiting Associate Professor from March 1998. Invited by Professor and Chairman Clifford B. Saper, Department of Neurology, Harvard Medical School, Harvard University, Massachusetts, USA
1997- 10 months Associate Professor from June 1997 Department of Physiology, Medical Faculty, University of Bergen Bilateral collab. and agreement exchange from 2002 until today - > 50 studs. *
1990-1994: Research fellow, Department of Physiology, Medical Faculty, University of Bergen
1989-1990: Senior Executive Officer at the Norwegian Research Council for Science and Humanities, Council for Medical Research (NRC, CMR), Oslo, Norway
1988-1989: Scientist/Researcher at The Norwegian Medicine Control Authority, Oslo, Norway
FELLOWSHIPS, AWARDS AND PRIZES (if applicable)
2013 Equality-award from Bergen University College, Norway, 2012 Prof. qualification stipend from, Faculty og Engineering, Bergen University College, 2009 Lecturing-Milieu Award for Student-active Research at the Biomedical Laboratory Science Program at Bergen University College, Norway
1998 3-year grant Research Council of Norway, Division of Medicine and Health, Norway
1998 Sleep Research Society Award for Sleep Workshop: Molecular and Cellular Foundations of Sleep Disorders, LA, CA.
1997 Sleep Research Society Award for Sleep Workshop; Molecular Biological Studies of Sleep, Program for Basic Sleep Research, LA, CA.
1995 Fulbright Fellowship - Research/Lecturing Award from U.S. - Norway Fulbright Foundation, for research at Department of Psychiatry, Harvard University
1995 US-Norway Foundation; Scandinavia Scholarship Award
1995 Research Council of Norway, Division of Medicine and Health
1995 Sleep Research Society's travel fellowship for the World Federation of Sleep Research Society's International Conference
1993 Sleep Research Society's travel fellowship for the World Federation of Sleep
1994 Research Society's International Conference on the Cellular Consequences of Sleep
1991 Nordic Academy for Advanced Study, Award for One month at Department of Pharmacology, Karolinska Institutet, Karolinska Sjukhuset, Stockholm invited by Professor Urban Ungerstedt
1992 European Sleep Research Society's Congress Grant
1988 The Royal Ministry of Administration and Consumer Affair, Norway
1985 European Training Program grant, European Science Foundation
MOBILITY (research stays abroad lasting more than three months) (if applicable)
1998-2000 Visiting Associate Professor from March 1998. Invited by Professor and Chairman Clifford B. Saper, Department of Neurology, Harvard Medical School, Harvard University, Massachusetts, USA
1995-1997 Research Fellow, Fulbright Foundation, Department of Psychiatry Harvard Medical School, Invited by Director and Chairman Professor Robert W. McCarley
SUPERVISION OF GRADUATE STUDENTS AND RESEARCH FELLOWS (if applicable)
2003-2005 Supervisor ”Appoint to the Doctoral Committee” for PhD-student Marta Helliesen at Union Institute and University, Cincinnati, Ohio, USA.
2013-2015 Supervisor for Master in Innovation and Entrepreneurship-student Beate Kluge, siv. Ing. And Head engineer at Haukeland University Hospital and University of Bergen, Norway, joint master between UiO and BUC/HiB. Master thesis: Implementering av ny teknologi i offentlige forsknings- og helsemiljø med impedansspektroskopi som eksempel.
2015-2016 Supervisor for Master Kristian Svinø Hestetun, Master’s thesis in Software Engineering at Department of Computing, Mathematics and Physics, Bergen University College and Department of Informatics, University of Bergen, Norway
2015-2016 Co-supervisor for Markus Lippert Karlsen, Master’s thesis in Software Engineering at Department of Computing, Mathematics and Physics, Bergen University College and Department of Informatics, University of Bergen, Norway
2018- PhD-co-supervisor for NN ad Simulation and tissue engineering, University of Bergen and Western Norway University of Applied Sciences, Bergen, Norway
TEACHING ACTIVITIES (if applicable)
2002-2022 Supervising 2-3 bachelor-group projects pr. Year in Biomedical Analytical Scientist education as part of 15-20 credits (ECTS) EVERY spring, Lecturing 10 ECTS in Anatomy and Physiology every autumn, Faculty of Engineering, Biomedical Laboratory Sciences Program, Bergen University College, Norway AND from 2017 by a new name: Faculty of Engineering and Science, Western Norway University of Applied Sciences, Bergen, Norway. Also, lecturing Cell biology 10 ECTS partly and now fully every spring semester from 2021.
1999-2001 25 % teaching/lecturing and other mandate work, Department of Physiology, Medical Faculty, University of Bergen, Norway. 1997 50 % teaching and other mandate work, Department of Physiology, Medical Faculty, University of Bergen, Norway
1990-1994 25% teaching and other mandate work, Department of Physiology, Medical Faculty,
University of Bergen
1991-1993 Physiology, lab. course and lecturing, 5 credit course for science students, master level, 3 days each year
1990-1993 Physiology, lab. course and lecturing, medical and dentistry studs., 3 weeks each year
1991-1992 Part time lecturer (50%) University Hospital Nursing School; in physiology and anatomy. 60 hours lecturing per semester pr. class, total 120 hours (two classes)
ORGANISATION OF SCIENTIFIC MEETINGS (if applicable)
2008 Initiated, organized and chaired a symposium and talk at the 19th Congress of the European Sleep Research Society, Glasgow, UK,
1999 Initiated, organizing and Chairman of one Symposium, one Focus Group and one Workshop on World Federation of Sleep Research Societies (WFSRS) Third International Congress, Dresden, Germany
1997 Scientific and organizing Head of the international meeting; In vivo Microdialysis in The Central Nervous System in Animals and Humans, December 6-7, 1997 at the Department of Physiology, University of Bergen, Norway
INSTITUTIONAL RESPONSIBILITIES
2002-2024 Head of R&D Cell stress group ad sleep deprivation, MRI- and hyperbaric cellular stress, 2018-2022 Head of Biomedical laboratory Sciences BIOMARG-research group,
PROJECT MANAGEMENT EXPERIENCE
2002-2024 Head/Project leader of three main projects: Proteomic changes in serum and saliva and or cells after cellar stress in sleep-deprivation project (humans), also a hyperbar-project (animal, human planned) and a MRI-project (human and cellular models). Main title first project: Protein markers for cell stress after shiftwork, a model for stress on the organism - a proteomic and systems biological study
COMMISSIONS OF TRUST
20015- 2017 Member of Scientific Advisory Board for Computer Science, Software Engineering, Sensor Networks and Engineering Computing at Western Norway University of Applied Sciences, Bergen, Norway
MEMBERSHIPS OF ACADEMIES / SCIENTIFIC SOCIETIES (if applicable)
1997- Reviewer for Sleep Research Online
2003 Ad hoc reviewer in Psychopharmacology
2006 Ad hoc reviewer in Brain Research Bulletin
2007- Reviewer for Bioingeniøren, Norwegian Biomedical Scientific Journal
2018 Ad hoc reviewer for Journal of Proteomics
2021 Ad hoc reviewer for Molecular Neurobiology
MAJOR SCIENTIFIC AND EDUCATIONAL COLLABORATIONS
2008 – present Professor Allan Pack and Assoc. prof. Nirinjini Naidoo, University of Pennsylvania School of medicine, Center for Sleep and Respiratory Neurobiology, Pennsylvania, USA,
2005 - present Director and Chairman Professor Robert W. McCarley and Professor and Chairman Clifford B. Saper, Dept. of Psychiatry and Dept. of Neurology respectively (cellular sleep mechanisms), Harvard Medical School, Harvard University, Massachusetts, USA and VA-administration Hospital and Beth Israel Hospital respectively.
2005 – present Prof. Gabor Juhasz, Laboratory of Proteomics, Department of Physiology and Neurobiology (neuroproteomics in animal models for altered sleep and neurological disorders), ELTE Eötvös Loránd University, Budapest, Hungary
Original scientific publications with referee (total 25) - 10 selected, SEE FULL LIST ALSO pop.vit.:
9Porkka-Heiskanen, T., Strecker, R.E., Thakkar, M., Bjørkum, A.A., Green, R. W. and McCarley R.W. Adenosine; A Mediator of the Sleep-Inducing Effects of Prolonged Wakefulness, Science, 1997, 276, (5316), iss. of 23 May, pp. 1265-1268. Citations: 1199
12 Chou, T, Bjørkum, A.A., Lu, J., Scammell, T. and Saper, C.B.; Afferents to the ventrolateral preoptic nucleus. J Neurosci. 2002 Feb 1;22(3):977-990. Citations: 287
13 Lu, J., Bjørkum, A.A., Xu, M., Gaus, S.E., Shiromani, P. and Saper, C.B.; Selective Activation of the Extended Ventrolateral Preoptic Nucleus during Rapid Eye Movement Sleep. , J Neurosci. 2002 Jun 1;22(11): 4568-4576. Citations: 304
14 B Bjorvatn, J Grønli, F Hamre, E Sørensen, E Fiske, AA Bjørkum, CM Portas, C.M, and R Ursin. Effects of sleep deprivation on extracellular serotonin in hippocampus and frontal cortex of the rat
Neuroscience 113 (2), 323-330. Citations: 66
10 Strecker, R.E., Thakkar, M.M., Porkka-Heiskanen, T., Dauphin, L.J., Bjørkum, A.A. and McCarley R.W. Behavioral state-related changes of extracellular serotonin consentration in the pedunculopontine tegmental nucleus: A microdialysis study in freely moving animals. Sleep Research Online 2(2): 21‑27, 1999. Citations: 46
18 Shea JL, Mochizuki T, Sagvaag V, Aspevik T, Bjorkum AA, Datta S. Rapid eye movement (REM) sleep homeostatic regulatory processes in the rat: changes in the sleep-wake stages and electroencephalographic power spectra. Brain Res. 2008 Jun 5;1213:48-56. Epub 2008 Apr 7. Citations: 53
19 Takács E, Nyilas R, Szepesi Z, Baracskay P, Karlsen B, Røsvold T, Bjørkum AA, Czurkó A, Kovács Z, Kékesi AK, Juhász G. Matrix metalloproteinase-9 activity increased by two different types of epileptic seizures that do not induce neuronal death: a possible role in homeostatic synaptic plasticity.
Neurochem Int. 2010 May-Jun;56(6-7):799-809. Citations: 60
21 Arthurs OJ, Bjørkum AA. Safety in pediatric imaging: an update. Acta Radiol. 2013 Nov;54(9):983-90. Citations: 6
22 Kristensen, T., Jacobsen, V. and Bjørkum A.A. Data Clustering with Visualization of Proteomics Data, 2014, Lambert Academic Publishing, ISBN 978-3-659-31829-0 (book). Citations: ?
23 Arvid Hope, Linda B. Stuhr, Tina Pavlin, Alvhild Alette Bjørkum, Marit Grønning. MRI of the central nervous system in rats following heliox saturation decompression. Undersea and Hyperbaric Medical Journal. 2015 Jan./Feb. 42(1):57-64. Citations: 1
24 Bjørkum AA, Oveland E, Stuhr L, Havnes MB, Berven F, Grønning M, Hope A. Fast hyperbaric decompression after heliox saturation altered the brain proteome in rats. PLoS One. 2017 Oct 4;12(10):e0185765. doi: 10.1371/journal.pone.0185765. eCollection 2017.PMID:28977037 Free Article Citations: 1
25 Bjørkum A.A., Carrasco Duran, A., Frode, B. et al. Human blood serum proteome changes after 6 hours of sleep deprivation at night. Sleep Science Practice 5, 14 (2021). https://doi.org/10.1186/s41606-021-00066-2
26. N. Musthafa, H.-S.; Walker, J.; Rahman, T.; Bjørkum, A.; Mustafa, K.; Velauthapillai, D. In-Silico Prediction of Mechanical Behaviour of Uniform Gyroid Scaffolds Affected by Its Design Parameters for Bone Tissue Engineering Applications. Computation 2023, 11, 181. https://doi.org/10.3390/computation11090181
27. Bjørkum AA, Griebel L, Birkeland E. Human serum proteomics reveals a molecular signature after one night of sleep deprivation. Sleep Adv. 2024 Jun 19;5(1): zpae042. doi: 10.1093/sleepadvances/zpae042. PMID: 39131770; PMCID: PMC11310596.
3. Research monographs and any translations thereof
1Ursin, R., Bjorvatn, B., Sommerfelt, L., Neckelmann, D. and Bjørkum, A. A. Studies on sleep-waking effects of serotonin reuptake inhibitors and receptor subtype involvement. Journal of Sleep Research, 1992, 1, 157-162. Citations: 8
2McCarley RW, Strecker, RE, Porkka-Heiskanen, T, Thakkar, M, Bjørkum, AA, Portas, CM, Rainnie, DG and Green, RW. Modulation of cholinergic neurons by serotonin and adenosine in the control of REM and Non-REM sleep. In Hayaishi O and Inoué S, eds. Sleep and Sleep Disorders:From Molecule to Behavior. Tokyo: Academic Press/Harcourt Brace Japan, 1997, pp 63 79. Citations: ?
3 Bjørkum, A.A., Pallesen, S. Holsten, F, Bjorvatn, B. Skiftarbeid og ulykker – relevans for offshoreindustrien, Tidsskr Nor Lægeforen, 2004; 124(21):2773-5, review. Citations: 5
4 Pallesen, S. Holsten, F, Bjørkum,A.A. , Bjorvatn, B. Søvnvansker ved nattarbeid, et problem for offshoreindustrien? Tidsskr Nor Lægeforen , 2004; 124(21):2770-2, review. Citations: 6
7. Major contributions to the early careers of excellent researchers (if applicable)
Prof. dr. med Bjørn Bjorvatn, prof. Dr. sci. Janne Grønli (supervision together with prof. Dr. med Reidun Ursin). Also 2 years of contribution and supervision in the groups of Dr. med. prof and Chairmen’s; Robert W. McCarley, Harvard Medical School, Dept. of Psychiatry, Laboratory of Neuroscience and Clifford B. Saper, Department of Neurology, Harvard Medical School, Harvard University, Massachusetts, USA
8. Examples of leadership in industrial innovation or design
Co-leadership with prof/dosent emeritus Terje Kristensen of Pattern Solutions https://www.patternsolutions.no/
Inventor of Bjørkum BrainTrain Center – sleep, circadian, learning and memory training